Alcian blue

Alcian blue

Chembox new
ImageFile = AlcianBlue.png ImageSize = 250px
IUPACName =
OtherNames = Alcian blue 8GX, Ingrain blue 1, C.I. 74240
Section1 = Chembox Identifiers
CASNo = 33864-99-2
PubChem = 3084579
SMILES = CN(C)C(= [N+] (C)C)SCC1=CC2=C(C=C1)C3=NC4=NC(=NC5=C6C=C (C=CC6=C( [N-] 5)N=C7C8=C(C=CC(=C8)CSC(= [N+] (C)C)N(C)C)C(=N7) N=C2 [N-] 3)CSC(= [N+] (C)C)N(C)C)C9=C4C=CC(=C9)CSC(= [N+] (C)C)N(C)C. [Cl-] . [Cl-] . [Cl-] . [Cl-] . [Cu+2]
InChI = 1/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33- 17-21-37-41(25-33)49-58-45(37)57-46-38-22-18-35(31-75-55 (69(9)10)70(11)12)27-43(38)51(59-46)64-52-44-28-36(32-76- -56(71(13)14)72(15)16)20-24-40(44)48(63-52)62-50-42-26- 34(19-23-39(42)47(60-49)61-50)30-74-54(67(5)6)68(7)8;;;;;/h17- -28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4/fC56H68N16S4.4 Cl.Cu/h;4*1h;/qm;4*-1;m
Section2 = Chembox Properties
C=56|H=68|Cl=4|Cu=1|N=16|S=4
Appearance =
Density =
MeltingPt =
BoilingPt =
Solubility =
Section3 = Chembox Hazards
MainHazards =
FlashPt =
Autoignition =

:"Alcian Blue is also a name of a noise pop band which broke up in 2006. [http://www.alcianblue.net/]

Alcian blue (AB), also called Alcian blue 8GX, Ingrain blue 1, and C.I. 74240, is a phthalocyanine dye that contains copper. The dye stains acid mucopolysaccharides and glycosaminoglycans, for which it is one of the most widely used cationic dyes; the stained parts are blue to bluish-green. It can be combined with H&E staining and van Gieson staining methods. It bonds by electrostatic forces with the negatively charged macromolecules. Gradual increases in the electrolyte concentration used to wash the bound dye selectively identifies neutral, sulphated, and phosphated mucopolysaccharides.

External links

* [http://www.lab.anhb.uwa.edu.au/mb140/MoreAbout/stains.htm Histological Stains]
* [http://stainsfile.info/StainsFile/dyes/74240.htm Stains File]
* [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1177474 The quantitative measurement of Alcian Blue–glycosaminoglycan complexes]


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