Collybistin

Collybistin is a protein much like gephyrin which is thought to aid the formation of submembrane gephyrin aggregates that accumulate hetero-oligomeric glycine receptors. Data from Nature Neuroscience 2000 suggests that the expression of collybistin regulates the membrane disposition of gephyrin by activating a GTPase of the Rho/Rac Family. Therefore this protein may be an important determinant of inhibitory postsynaptic membrane formation and plasticity.^[1]

References

1. ^ Betz, Heinrich; Kins, Stefan; Kirsch, Joachim (2000). "Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin.". Nature Neuroscience 3 (1): 22–9. doi:10.1038/71096. PMID 10607391. http://www.nature.com/neuro/journal/v3/n1/full/nn0100_22.html. 

This protein-related article is a stub. You can help Wikipedia by expanding it.v · Categories: GTP-binding protein regulators Protein stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? Collybiopsis Collymore Look at other dictionaries: ARHGEF9 — Cdc42 guanine nucleotide exchange factor (GEF) 9, also known as ARHGEF9, is a human gene.cite web | title = Entrez Gene: ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia GPHN — Gephyrin, also known as GPHN, is a human gene.cite web | title = Entrez Gene: GPHN gephyrin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=10243| accessdate = ] PBB Summary section title = summary text =… …   Wikipedia Gephyrin — is a protein that is a component of the postsynaptic protein network of inhibitory synapses. Positive antibody staining for gephyrin at a synapse is consistent with the presence of glycine and/or GABA A receptors. Gephyrin displaces GABA… …   Wikipedia GLRB — Glycine receptor, beta, also known as GLRB, is a human gene.cite web | title = Entrez Gene: GLRB glycine receptor, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2743| accessdate = ] PBB Summary… …   Wikipedia ARHGEF4 — Rho guanine nucleotide exchange factor (GEF) 4, also known as ARHGEF4, is a human gene.cite web | title = Entrez Gene: ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”