Chorangiosis

Chorangiosis
Classification and external resources
Micrograph of a chorangiosis. H&E stain.

Chorangiosis is a placental pathology characterized by an abundance of blood vessels within the chorionic villi.

Associations

It is associated with gestational diabetes,^[1] smoking and high altitude.

Diagnosis

It is diagnosed by a microscopic examination of the placenta.

Commonly used criteria from Altshuler^[2][3] are: "a minimum of 10 villi, each with 10 or more vascular channels, in 10 or more areas of 3 or more random, non-infarcted placental areas when using a ×10 ocular." The Altshuler criteria are not theoretically rigorous, as they do not define the area. Normal villi have up to five vascular channels.^[3]

See also

• Chorangioma

Additional images

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  Intermed. mag.

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  Very high mag.

References

1. ^ Daskalakis, G.; Marinopoulos, S.; Krielesi, V.; Papapanagiotou, A.; Papantoniou, N.; Mesogitis, S.; Antsaklis, A. (2008). "Placental pathology in women with gestational diabetes.". Acta Obstet Gynecol Scand 87 (4): 403–7. doi:10.1080/00016340801908783. PMID 18382864. 
2. ^ Altshuler, G. (Jan 1984). "Chorangiosis. An important placental sign of neonatal morbidity and mortality.". Arch Pathol Lab Med 108 (1): 71–4. PMID 6546343. 
3. ^ ^{a b} De La Ossa, MM.; Cabello-Inchausti, B.; Robinson, MJ. (Sep 2001). "Placental chorangiosis.". Arch Pathol Lab Med 125 (9): 1258. doi:10.1043/0003-9985(2001)1251258:PC2.0.CO;2. PMID 11520290. http://www.archivesofpathology.org/doi/full/10.1043/0003-9985%282001%29125%3C1258:PC%3E2.0.CO;2.