Chlorobi-RRM RNA motif

Chlorobi-RRM RNA
Consensus secondary structure of Chlorobi-RRM RNAs
Identifiers
Symbol	Clorobi-RRM
Rfam	RF01697
Other data
RNA type	Cis-regulatory element
Domain(s)	Chlorobi

The Chlorobi-RRM RNA motif is a conserved RNA structure identified by bioinformatics.^[1] It is found within bacteria in the phylum Chlorobi, and is exclusively detected in the presumed 5' untranslated regions (5' UTRs) of genes that encode putative RNA-binding proteins. Since many RNA-binding proteins regulate their own expression in a feedback mechanism by binding or acting up their 5' UTR, it was proposed that the Chlorobi-RRM is a component in an analogous feedback mechanism. Structurally, the motif consists of two stem-loops, the second of which might function as a rho-independent transcription terminator.

References

1. ^ Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2864571. 

External links

• Rfam page for Chlorobi-RRM RNA