Channelosome

Channelosome

The channelosome (not to be confused with "channelome") is the collection of (usually) signalling proteins associated with an ion channel. The channelosome is frequently clustered within a lipid microdomain or caveolae. This collection of proteins may be involved with anchoring, phosphorylation or some other modulatory or support function. An example is neural KCNQ/M (Kv7) potassium channelosome (see Delmas & Brown, 2005).

References

Delmas, P.; Brown, D. A. (2005). "Pathways modulating neural KCNQ/M (Kv7) potassium channels". Nature Reviews Neuroscience 6 (11): 850. doi:10.1038/nrn1785. PMID 16261179.  edit


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”