Rs1800532

Infobox Single nucleotide polymorphism
rsid = 1800532
name_1 = A218C
region = Intron 7
gene = TPH1In genetics, rs1800532 (A218C) is a genetic variant. It is a single nucleotide polymorphism in the "TPH1" gene and located in intron 7.

It has been examined in relation to personality traits. [Cite journal
author = Shih-Jen Tsai, Ying-Chieh Wang, Jen-Yeu Chen & Chen-Jee Hong
title = Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits
journal = Neuropsychobiology
volume = 48
issue = 2
pages = 68–61
year = 2003
month =
doi = 10.1159/000072879
pmid = 14504413] [Cite journal
author = Ion Anghelescu, Christoph Klawe, Christoph Fehr, Peter Singer, Alexandra Schleicher, Hubertus Himmerich, Christoph Hiemke, Norbert Dahmen & Armin Szegedi
title = The TPH intron 7 A218C polymorphism and TCI dimension scores in alcohol-dependent patients: hints to nonspecific psychopathology
journal = Addictive behaviors
volume = 30
issue = 6
pages = 1135–1133
year = 2005
month = July
doi = 10.1016/j.addbeh.2004.11.002
pmid = 15925123] [Cite journal
author = Akihito Suzuki, Takashi Fukasawa, Hiroaki Shiraishi, Genki Ishii, Shingo Oshino, Toshiaki Aoshima & Koichi Otani
title = No association between the TPH A218C polymorphism and personality traits in Japanese healthy subjects
journal = Progress in neuro-psychopharmacology & biological psychiatry
volume = 31
issue = 2
pages = 395–398
year = 2007
month = March
doi = 10.1016/j.pnpbp.2006.10.003
pmid = 17116352]

A779C is another SNP in same intron.

Reference