Heron HBV RNA encapsidation signal epsilon

The Heron HBV RNA encapsidation signal epsilon is an RNA structure that is shown to facilitate encapsidation of the pregenomic RNA required for replication.

The HHBV epsilon consists of a stem structure, a bulge and an apical stem-loop. The RNA structure has been determined by chemical probing and by mutagenesis [cite journal| title= Sequence- and structure-specific determinants in the interaction between the RNA encapsidation signal and reverse transcriptase of avian hepatitis B viruses. | id = PMID 9188560] .A recent NMR analysis of the HHBV epsilon have shown that the apical loop to be capped by a stable well-structured UGUU tetraloop [cite journal| title= Thermodynamics and NMR studies on Duck, Heron and Human HBV encapsidation signals | id = PMID 17430968] .

The Rfam structure is based on a covariation model.

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Related Entries

HBV RNA encapsidation signal epsilon

Duck HBV RNA encapsidation signal epsilon