Duck HBV RNA encapsidation signal epsilon

Duck HBV RNA encapsidation signal epsilon

The Duck HBV RNA encapsidation signal epsilon is an RNA structure that is shown to facilitate encapsidation of the pregenomic RNA required for replication.

DHBV is used as a model to understand human HBV. DHBV epsilon consists of a stem structure, a bulge and an apical stem loop. The RNA structure was determined by chemical probing, NMR analysis and by mutagenesis [cite journal| title= The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function | id = PMID 9776740] .

A recent NMR analysis of the DHBV epsilon have shown that the apical loop to be capped by a stable well-structured UGUU tetraloop [cite journal| title= Thermodynamics and NMR studies on Duck, Heron and Human HBV encapsidation signals | id = PMID 17430968] .

The Rfam structure is based on a covariation model.

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HBV RNA encapsidation signal epsilon


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  • Avian HBV RNA encapsidation signal epsilon — Fig. 1. Duck HBV RNA encapsidation signal epsilon Fig. 2. Heron HBV RNA encapsidation signal epsi …   Wikipedia

  • Heron HBV RNA encapsidation signal epsilon — The Heron HBV RNA encapsidation signal epsilon is an RNA structure that is shown to facilitate encapsidation of the pregenomic RNA required for replication.The HHBV epsilon consists of a stem structure, a bulge and an apical stem loop. The RNA… …   Wikipedia

  • Hepatitis B virus — For the disease, see Hepatitis B. Hepatitis B virus TEM micrograph showing hepatitis B viruses Virus classification Group …   Wikipedia

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