Hepatitis B virus PRE alpha

Hepatitis B virus PRE alpha

The Hepatitis B virus PREalpha (HBV PREalpha) is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs.

HBV PREalpha consists of a 30 nt stem-loop, with a 5 nt apical loop. The conserved stem-loop was predicted within the HBV PRE sequence and confirmed by mutagenesis. [cite journal| title= The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function | id = PMID 9776740] .The Rfam structure is based on a covariation model.

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