WNT2

protein
Name = wingless-type MMTV integration site family, member 2
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HGNCid = 12780
Symbol = WNT2
AltSymbols = INT1L1
EntrezGene = 7472
OMIM = 147870
RefSeq = NM_003391
UniProt = P09544
PDB =
ECnumber =
Chromosome = 7
Arm = q
Band = 31
LocusSupplementaryData =

Wingless-type MMTV integration site family, member 2, also known as WNT2, is a human gene.cite web | title = Entrez Gene: WNT2 wingless-type MMTV integration site family, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7472| accessdate = ] cite journal | author = Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS | title = Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless | journal = EMBO J. | volume = 7 | issue = 6 | pages = 1743–8 | year = 1988 | month = June | pmid = 2971536 | pmc = 457162 | url = | issn = ]

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins which are involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.

References