Purple glove syndrome

Purple Glove Syndrome (PGS) is a poorly understood skin disease in which the extremities become swollen, discoloured and painful.cite journal |author=Chokshi R, Openshaw J, Mehta NN, Mohler E |title=Purple glove syndrome following intravenous phenytoin administration |journal=Vasc Med |volume=12 |issue=1 |pages=29–31 |year=2007 |month=February |pmid=17451091 |doi= |url=http://vmj.sagepub.com/cgi/pmidlookup?view=long&pmid=17451091] PGS is potentially serious, and may require amputation. PGS is most common among elderly patients and those receiving large, multiple intravenous doses of the epilepsy drug phenytoin.cite journal |author=O'Brien TJ, Cascino GD, So EL, Hanna DR |title=Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin |journal=Neurology |volume=51 |issue=4 |pages=1034–9 |year=1998 |month=October |pmid=9781525 |doi= |url=]

Footnotes

External links

* [http://www.fda.gov/cder/aers/potential_signals/potential_signals_2008Q1.htm FDA] : Potential Signals of Serious Risks/New Safety Information Identified by the Adverse Event Reporting System (AERS) -- January - March 2008