Laterodorsal tegmental nucleus
- Laterodorsal tegmental nucleus
Infobox Brain
Name = PAGENAME
Latin = nucleus tegmentalis posterolateralis
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BrainInfoType = ancil
BrainInfoNumber = 282
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DorlandsPre = n_11
DorlandsSuf = 12583635
The laterodorsal tegmental nucleus (or lateroposterior tegmental nucleus) is a nucleus situated in the brainstem, spanning the midbrain tegmentum and the pontine tegmentum.
Function
The laterodorsal tegmental nucleus sends cholinergic (acetylcholine) projections to many subcortical and cortical structures, including the thalamus, hypothalamus, substantia nigra (dopamine neurons), ventral tegmental area (dopamine neurons), cortex (with bidirectional connections with the prefrontal cortex).
The laterodorsal tegmental nucleus may be involved in modulating sustained attention or in mediating alerting responses, and also in the generation of REM sleep (along with the pedunculopontine nucleus).
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