HLA-B44

HLA-B44 (B44) is an HLA-B serotype. The serotype identifies the B*44 gene-allele protein products of HLA-B.cite journal | author = Marsh SG, Albert ED, Bodmer WF, "et al" | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x]

B44 is a of the B12, and is a sister type of B45.

erotype

Alleles

Disease

HLA-B44 increases recurrent sinopulmonary infections.cite journal |author=Johnston DT, Mehaffey G, Thomas J, "et al" |title=Increased frequency of HLA-B44 in recurrent sinopulmonary infections (RESPI) |journal=Clin. Immunol. |volume=119 |issue=3 |pages=346–50 |year=2006 |month=June |pmid=16542878 |doi=10.1016/j.clim.2006.02.001 |url=] Protective effects: HLA-B44 appears to be protective against autoimmune lymphoproliferative syndrome in patients with C95 defect (ALPS type Ia).cite journal |author=Vacek MM, Schäffer AA, Davis J, "et al" |title=HLA B44 is associated with decreased severity of autoimmune lymphoproliferative syndrome in patients with CD95 defects (ALPS type Ia) |journal=Clin. Immunol. |volume=118 |issue=1 |pages=59–65 |year=2006 |month=January |pmid=16257267 |doi=10.1016/j.clim.2005.09.006 |url=] B44 may be a cofactor in ankylosing spondylitiscite journal |author=Purrmann J, Zeidler H, Bertrams J, "et al" |title=HLA antigens in ankylosing spondylitis associated with Crohn's disease. Increased frequency of the HLA phenotype B27,B44 |journal=J. Rheumatol. |volume=15 |issue=11 |pages=1658–61 |year=1988 |month=November |pmid=3266250 |doi= |url=]

References