- GABRQ
protein
Name = gamma-aminobutyric acid (GABA) receptor, theta
caption =
width =
HGNCid = 14454
Symbol = GABRQ
AltSymbols =
EntrezGene = 55879
OMIM = 300349
RefSeq = NM_018558
UniProt = Q9UN88
PDB =
ECnumber =
Chromosome = X
Arm = q
Band = 28
LocusSupplementaryData =Gamma-aminobutyric acid (GABA) A receptor, theta, also known as GABRQ, is a human
gene .cite journal | author = Sinkkonen ST, Hanna MC, Kirkness EF, Korpi ER | title = GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus | journal = J. Neurosci. | volume = 20 | issue = 10 | pages = 3588–95 | year = 2000 | month = May | pmid = 10804200 | url = http://www.jneurosci.org/cgi/pmidlookup?view=long&pmid=10804200 | issn = ] cite journal | author = Bonnert TP, McKernan RM, Farrar S, le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Brown N, Wafford KA, Whiting PJ | title = theta, a novel gamma-aminobutyric acid type A receptor subunit | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 96 | issue = 17 | pages = 9891–6 | year = 1999 | month = August | pmid = 10449790 | pmc = 22306 | url = http://www.pnas.org/cgi/pmidlookup?view=long&pmid=10449790 | issn = ] Theprotein encoded by this gene is a subunit of theGABAA receptor .The θ subunit has highest sequence similarity with the β1 subunit. This subunit coassembles with
* α2, β1, and γ1
* α3 and β1cite journal | author = Ranna M, Sinkkonen ST, Möykkynen T, Uusi-Oukari M, Korpi ER | title = Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes | journal = BMC Pharmacol. | volume = 6 | issue = | pages = 1 | year = 2006 | pmid = 16412217 | pmc = 1363348 | doi = 10.1186/1471-2210-6-1 | url = | issn = ]
* α3, β1, and εReferences
External links
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