GENSCAN

GENSCAN

GenScan is an online program to identify complete gene structures in genomic DNA. It is a GHMM-based gene finder for human sequences.The Web server at the MIT can be found at: http://genes.mit.edu/GENSCAN.html

GENSCAN was developed by Chris Burge in the research group of Samuel Karlin, Department of Mathematics, Stanford University.

An overview over similar software can be found at: http://www.genefinding.org/software.html

References

* Burge, C. and Karlin, S. (1997) Prediction of complete gene structures in human genomic DNA. J. Mol. Biol. 268, 78-94. PMID: 9149143.
* Burge, C. B. (1998) Modeling dependencies in pre-mRNA splicing signals. In Salzberg, S., Searls, D. and Kasif, S., eds. Computational Methods in Molecular Biology, Elsevier Science, Amsterdam, pp. 127-163.
* Burge, C. B. and Karlin, S. (1998) Finding the genes in genomic DNA. Curr. Opin. Struct. Biol. 8, 346-354. PMID: 9149143.


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