CGP 52608

CGP 52608

chembox new
ImageFile = CGP_52608.png ImageSize = 200
IUPACName = 3-Methyl-1- [(4-oxo-3-prop-2-enyl-1,3-thiazolidin-2-ylidene)amino] thiourea
OtherNames =
Section1 = Chembox Identifiers
CASNo=87958-67-6
PubChem=6509863
SMILES=O=C(N/1CC=C)CSC1=N/NC(NC)=S

Section2 = Chembox Properties
Formula=C8H12N4OS2
MolarMass=244.34 g/mol
Appearance=
Density=
MeltingPt=
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Solubility=

Section3 = Chembox Hazards
MainHazards=
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CGP 52608 is a selective ligand of the RAR-related orphan receptor alpha.cite journal | author = Wiesenberg I, Missbach M, Kahlen JP, Schräder M, Carlberg C | title = Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand | journal = Nucleic Acids Res. | volume = 23 | issue = 3 | pages = 327–33 | year = 1995 | month = February | pmid = 7885826 | pmc = 306679 | doi = 10.1093/nar/23.3.327 | url = | issn = ] CGP 52608 has also been reported to possess antiarthritic activity.cite journal | author = Missbach M, Jagher B, Sigg I, Nayeri S, Carlberg C, Wiesenberg I | title = Thiazolidine diones, specific ligands of the nuclear receptor retinoid Z receptor/retinoid acid receptor-related orphan receptor alpha with potent antiarthritic activity | journal = J. Biol. Chem. | volume = 271 | issue = 23 | pages = 13515–22 | year = 1996 | month = June | pmid = 8662835 | doi = 10.1074/jbc.271.23.13515 | url = | issn = ]

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Look at other dictionaries:

  • RAR-related orphan receptor — The RAR related orphan receptors (RORs) are members of the nuclear receptor family of intracellular transcription factors.cite journal | author = Giguère V, Tini M, Flock G, Ong E, Evans RM, Otulakowski G | title = Isoform specific amino terminal …   Wikipedia

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