AA amyloidosis

AA amyloidosis

AA amyloidosis is a form of amyloidosis associated with serum amyloid A protein (SAA), an acute-phase protein. cite journal |author=Lachmann HJ, Goodman HJ, Gilbertson JA, "et al" |title=Natural history and outcome in systemic AA amyloidosis |journal=N. Engl. J. Med. |volume=356 |issue=23 |pages=2361–71 |year=2007 |month=June |pmid=17554117 |doi=10.1056/NEJMoa070265 |url=]

Presentation

The common feature to conditions associated with reactive systemic amyloidosis is long-standing cell breakdown due to chronic inflammatory or disease processes.

Associated conditions

It is associated with chronic inflammatory conditions, including: rheumatoid arthritis, ankylosing spondylitis, Crohn disease, ulcerative colitis, tuberculosis, bronchiectasis, chronic osteomyelitis.

Other conditions include Hodgkin disease, renal cell carcinoma.

It can be associated with nephrotic syndrome.cite web |url=http://www.bu.edu/amyloid/doctors/features/clinical-aa.html |title=BU | Amyloid Treatment & Research Program | Doctors | Clinical Features | AA Amyloidosis |format= |work= |accessdate=]

References


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