21-hydroxysteroid dehydrogenase (NAD+)

21-hydroxysteroid dehydrogenase (NAD+)

In enzymology, a 21-hydroxysteroid dehydrogenase (NAD+) (EC number|1.1.1.150) is an enzyme that catalyzes the chemical reaction

:pregnan-21-ol + NAD+ ightleftharpoons pregnan-21-al + NADH + H+

Thus, the two substrates of this enzyme are pregnan-21-ol and NAD+, whereas its 3 products are pregnan-21-al, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 21-hydroxysteroid:NAD+ 21-oxidoreductase. This enzyme is also called 21-hydroxysteroid dehydrogenase (NAD+).

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37250-75-2."

Gene Ontology (GO) codes


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