Glyoxylate reductase

In enzymology, a glyoxylate reductase (EC number|1.1.1.26) is an enzyme that catalyzes the chemical reaction

:glycolate + NAD⁺ $ightleftharpoons$ glyoxylate + NADH + H⁺

Thus, the two substrates of this enzyme are glycolate and NAD⁺, whereas its 3 products are glyoxylate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycolate:NAD+ oxidoreductase. Other names in common use include NADH-glyoxylate reductase, glyoxylic acid reductase, and NADH-dependent glyoxylate reductase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2DBQ, PDB link|2DBR, and PDB link|2DBZ.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9028-32-4."

Gene Ontology (GO) codes