dCTP diphosphatase

dCTP diphosphatase
Identifiers
EC number	3.6.1.12
CAS number	9024-87-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a dCTP diphosphatase (EC 3.6.1.12) is an enzyme that catalyzes the chemical reaction

dCTP + H₂O $\rightleftharpoons$ dCMP + diphosphate

Thus, the two substrates of this enzyme are dCTP and H₂O, whereas its two products are dCMP and diphosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is dCTP nucleotidohydrolase. Other names in common use include deoxycytidine-triphosphatase, dCTPase, dCTP pyrophosphatase, deoxycytidine triphosphatase, deoxy-CTPase, and dCTPase. This enzyme participates in pyrimidine metabolism.

References

• Zimmerman SB and Kornberg A (1961). "Deoxycytidine di- and triphosphate cleavage by an enzyme formed in bacteriophage-infected Escherichia coli". J. Biol. Chem. 236: 1480–1486. PMID 13788541. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: EC 3.6.1 Enzymes of unknown structure Hydrolase stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать курсовую dCTP deaminase (dUMP-forming) DCT Gdańsk Look at other dictionaries: DCTP diphosphatase — In enzymology, a dCTP diphosphatase (EC number|3.6.1.12) is an enzyme that catalyzes the chemical reaction:dCTP + H2O ightleftharpoons dCMP + diphosphateThus, the two substrates of this enzyme are dCTP and H2O, whereas its two products are dCMP… …   Wikipedia dCTP deaminase (dUMP-forming) — Identifiers EC number 3.5.4.30 Databases IntEnz IntEnz view …   Wikipedia List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism …   Universalium 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”