Transposon Mutagenesis

Transposon Mutagenesis

Transposon mutagenesis or transposition mutagenesis is a biology process that allows genes to be transferred to a host organism's chromosome, interrupting or modifying the function of an extant gene on the chromosome and causing mutation.

History

Transposon mutagenesis was first studied by Barbara McClintock in the mid-20th century during her Nobel Prize-winning work with corn.

Dynamics

In the case of bacteria, transposition mutagenesis is usually accomplished by way of a plasmid from which a transposon is extracted and inserted into the host chromosome. This usually requires a set of enzymes including transposase to be translated.

External links

* [http://www.gmo-safety.eu/en/gene_transfer/elimination/10.docu.html Jumping genes: from phenomenon to tool]


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