- SLA2
Src-like-adaptor 2, also known as SLA2, is a human
gene .cite web | title = Entrez Gene: SLA2 Src-like-adaptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84174| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.cite web | title = Entrez Gene: SLA2 Src-like-adaptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84174| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Loreto MP, McGlade CJ |title=Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v. |journal=Oncogene |volume=22 |issue= 2 |pages= 266-73 |year= 2003 |pmid= 12527895 |doi= 10.1038/sj.onc.1206114
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Loreto MP, Berry DM, McGlade CJ |title=Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling. |journal=Mol. Cell. Biol. |volume=22 |issue= 12 |pages= 4241-55 |year= 2002 |pmid= 12024036 |doi=
*cite journal | author=Pandey A, Ibarrola N, Kratchmarova I, "et al." |title=A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling. |journal=J. Biol. Chem. |volume=277 |issue= 21 |pages= 19131-8 |year= 2002 |pmid= 11891219 |doi= 10.1074/jbc.M110318200
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Holland SJ, Liao XC, Mendenhall MK, "et al." |title=Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling. |journal=J. Exp. Med. |volume=194 |issue= 9 |pages= 1263-76 |year= 2001 |pmid= 11696592 |doi=PBB_Controls
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