CACNG1

CACNG1

Calcium channel, voltage-dependent, gamma subunit 1, also known as CACNG1, is a human gene.cite web | title = Entrez Gene: CACNG1 calcium channel, voltage-dependent, gamma subunit 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=786| accessdate = ]

PBB_Summary
section_title =
summary_text = L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes.cite web | title = Entrez Gene: CACNG1 calcium channel, voltage-dependent, gamma subunit 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=786| accessdate = ]

ee also

* Voltage-dependent calcium channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chu PJ, Robertson HM, Best PM |title=Calcium channel gamma subunits provide insights into the evolution of this gene family. |journal=Gene |volume=280 |issue= 1-2 |pages= 37-48 |year= 2002 |pmid= 11738816 |doi=
*cite journal | author=Burgess DL, Gefrides LA, Foreman PJ, Noebels JL |title=A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. |journal=Genomics |volume=71 |issue= 3 |pages= 339-50 |year= 2001 |pmid= 11170751 |doi= 10.1006/geno.2000.6440
*cite journal | author=Burgess DL, Davis CF, Gefrides LA, Noebels JL |title=Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. |journal=Genome Res. |volume=9 |issue= 12 |pages= 1204-13 |year= 2000 |pmid= 10613843 |doi=
*cite journal | author=Iles DE, Segers B, Weghuis DO, "et al." |title=Localization of the gamma-subunit of the skeletal muscle L-type voltage-dependent calcium channel gene (CACNLG) to human chromosome band 17q24 by in situ hybridization and identification of a polymorphic repetitive DNA sequence at the gene locus. |journal=Cytogenet. Cell Genet. |volume=64 |issue= 3-4 |pages= 227-30 |year= 1993 |pmid= 8404045 |doi=
*cite journal | author=Iles DE, Segers B, Sengers RC, "et al." |title=Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility. |journal=Hum. Mol. Genet. |volume=2 |issue= 7 |pages= 863-8 |year= 1993 |pmid= 8395940 |doi=
*cite journal | author=Powers PA, Liu S, Hogan K, Gregg RG |title=Molecular characterization of the gene encoding the gamma subunit of the human skeletal muscle 1,4-dihydropyridine-sensitive Ca2+ channel (CACNLG), cDNA sequence, gene structure, and chromosomal location. |journal=J. Biol. Chem. |volume=268 |issue= 13 |pages= 9275-9 |year= 1993 |pmid= 8387489 |doi=

External links

*

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  • Voltage-dependent calcium channel — Voltage dependent calcium channels (VDCC) are a group of voltage gated ion channels found in excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the ion Ca2+.[1][2] These channels are slightly permeable to sodium… …   Wikipedia

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