SEMA4G

SEMA4G

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G, also known as SEMA4G, is a human gene.cite web | title = Entrez Gene: SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57715| accessdate = ]

PBB_Summary
section_title =
summary_text = Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene and the gene for mitochondrial ribosomal protein L43 overlap at map location 10q24.31 and are transcribed in opposite directions.cite web | title = Entrez Gene: SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57715| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Pasterkamp RJ, Kolodkin AL |title=Semaphorin junction: making tracks toward neural connectivity. |journal=Curr. Opin. Neurobiol. |volume=13 |issue= 1 |pages= 79-89 |year= 2003 |pmid= 12593985 |doi=
*cite journal | author=Dickson BJ |title=Molecular mechanisms of axon guidance. |journal=Science |volume=298 |issue= 5600 |pages= 1959-64 |year= 2003 |pmid= 12471249 |doi= 10.1126/science.1072165
*cite journal | author=Holtmaat AJ, De Winter F, De Wit J, "et al." |title=Semaphorins: contributors to structural stability of hippocampal networks? |journal=Prog. Brain Res. |volume=138 |issue= |pages= 17-38 |year= 2002 |pmid= 12432760 |doi=
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375-81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Nagase T, Kikuno R, Nakayama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 4 |pages= 273-81 |year= 2001 |pmid= 10997877 |doi=

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Look at other dictionaries:

  • Semaphorin — Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short range inhibitory signals and signal through multimeric receptor complexes. They are usually cues to deflect… …   Wikipedia

  • Sema domain — Pfam box Symbol = Sema Name = width =250 caption =Sema domain, immunoglobulin domain (Ig), short basic domain Pfam= PF01403 InterPro= IPR001627 SMART= PROSITE = PDOC51004 SCOP = 1olz TCDB = OPM family= OPM protein= PDB=PDB3|1shyB:55 500… …   Wikipedia

  • Semaphorine — (griech. semaphor für Signal) sind eine Klasse von sekretierten oder Membran assoziierten Proteinen, die im Zentralnervensystem durch repulsive oder attraktive Interaktion mit Neuropilin und Plexin Rezeptoren an der axonalen Wegfindung beteiligt… …   Deutsch Wikipedia

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