CYP26B1

Cytochrome P450, family 26, subfamily B, polypeptide 1, also known as CYP26B1, is a human gene.cite web | title = Entrez Gene: CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56603| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.cite web | title = Entrez Gene: CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56603| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rat E, Billaut-Laden I, Allorge D, "et al." |title=Evidence for a functional genetic polymorphism of the human retinoic acid-metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida. |journal=Birth Defects Res. Part A Clin. Mol. Teratol. |volume=76 |issue= 6 |pages= 491-8 |year= 2006 |pmid= 16933217 |doi= 10.1002/bdra.20275
*cite journal | author=Bowles J, Knight D, Smith C, "et al." |title=Retinoid signaling determines germ cell fate in mice. |journal=Science |volume=312 |issue= 5773 |pages= 596-600 |year= 2006 |pmid= 16574820 |doi= 10.1126/science.1125691
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Trofimova-Griffin ME, Juchau MR |title=Developmental expression of cytochrome CYP26B1 (P450RAI-2) in human cephalic tissues. |journal=Brain Res. Dev. Brain Res. |volume=136 |issue= 2 |pages= 175-8 |year= 2002 |pmid= 12101034 |doi=
*cite journal | author=Abu-Abed S, MacLean G, Fraulob V, "et al." |title=Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. |journal=Mech. Dev. |volume=110 |issue= 1-2 |pages= 173-7 |year= 2002 |pmid= 11744378 |doi=
*cite journal | author=White JA, Ramshaw H, Taimi M, "et al." |title=Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 12 |pages= 6403-8 |year= 2000 |pmid= 10823918 |doi= 10.1073/pnas.120161397
*cite journal | author=Nelson DR |title=A second CYP26 P450 in humans and zebrafish: CYP26B1. |journal=Arch. Biochem. Biophys. |volume=371 |issue= 2 |pages= 345-7 |year= 1999 |pmid= 10545224 |doi= 10.1006/abbi.1999.1438

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