RNF125

RNF125

Ring finger protein 125, also known as RNF125, is a human gene.cite web | title = Entrez Gene: RNF125 ring finger protein 125| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54941| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.cite web | title = Entrez Gene: RNF125 ring finger protein 125| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54941| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Giannini AL, Gao Y, Bijlmakers MJ |title=T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain. |journal=Biochem. J. |volume=410 |issue= 1 |pages= 101-11 |year= 2008 |pmid= 17990982 |doi= 10.1042/BJ20070995
*cite journal | author=Shoji-Kawata S, Zhong Q, Kameoka M, "et al." |title=The RING finger ubiquitin ligase RNF125/TRAC-1 down-modulates HIV-1 replication in primary human peripheral blood mononuclear cells. |journal=Virology |volume=368 |issue= 1 |pages= 191-204 |year= 2007 |pmid= 17643463 |doi= 10.1016/j.virol.2007.06.028
*cite journal | author=Zhao H, Li CC, Pardo J, "et al." |title=A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation. |journal=J. Immunol. |volume=174 |issue= 9 |pages= 5288-97 |year= 2005 |pmid= 15843525 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Chu P, Pardo J, Zhao H, "et al." |title=Systematic identification of regulatory proteins critical for T-cell activation. |journal=J. Biol. |volume=2 |issue= 3 |pages= 21 |year= 2004 |pmid= 12974981 |doi= 10.1186/1475-4924-2-21
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Saurin AJ, Borden KL, Boddy MN, Freemont PS |title=Does this have a familiar RING? |journal=Trends Biochem. Sci. |volume=21 |issue= 6 |pages= 208-14 |year= 1996 |pmid= 8744354 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=

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  • RING finger domain — Pfam box Symbol = zf C3HC4 Name = Zinc finger, C3HC4 type (RING finger) width = caption = Pfam= PF00097 InterPro= IPR001841 SMART= PROSITE= PDOC00449 SCOP = 1chc TCDB = OPM family= OPM protein= PDB=PDB3|1jm7A:24 64 PDB3|1rmd :290 328 PDB3|1bor… …   Wikipedia

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