BEST2

Bestrophin 2, also known as BEST2, is a human gene.cite web | title = Entrez Gene: BEST2 bestrophin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54831| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon.cite web | title = Entrez Gene: BEST2 bestrophin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54831| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Pifferi S, Pascarella G, Boccaccio A, "et al." |title=Bestrophin-2 is a candidate calcium-activated chloride channel involved in olfactory transduction. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 34 |pages= 12929-34 |year= 2006 |pmid= 16912113 |doi= 10.1073/pnas.0604505103
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Tsunenari T, Sun H, Williams J, "et al." |title=Structure-function analysis of the bestrophin family of anion channels. |journal=J. Biol. Chem. |volume=278 |issue= 42 |pages= 41114-25 |year= 2003 |pmid= 12907679 |doi= 10.1074/jbc.M306150200
*cite journal | author=Stöhr H, Marquardt A, Nanda I, "et al." |title=Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. |journal=Eur. J. Hum. Genet. |volume=10 |issue= 4 |pages= 281-4 |year= 2002 |pmid= 12032738 |doi= 10.1038/sj.ejhg.5200796
*cite journal | author=Sun H, Tsunenari T, Yau KW, Nathans J |title=The vitelliform macular dystrophy protein defines a new family of chloride channels. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 6 |pages= 4008-13 |year= 2002 |pmid= 11904445 |doi= 10.1073/pnas.052692999
*cite journal | author=Marquardt A, Stöhr H, Passmore LA, "et al." |title=Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best's disease). |journal=Hum. Mol. Genet. |volume=7 |issue= 9 |pages= 1517-25 |year= 1998 |pmid= 9700209 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=

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