BRWD1

Bromodomain and WD repeat domain containing 1, also known as BRWD1, is a human gene.cite web | title = Entrez Gene: BRWD1 bromodomain and WD repeat domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54014| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends.cite web | title = Entrez Gene: BRWD1 bromodomain and WD repeat domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54014| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hu YH, Warnatz HJ, Vanhecke D, "et al." |title=Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. |journal=BMC Genomics |volume=7 |issue= |pages= 155 |year= 2006 |pmid= 16780588 |doi= 10.1186/1471-2164-7-155
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Huang H, Rambaldi I, Daniels E, Featherstone M |title=Expression of the Wdr9 gene and protein products during mouse development. |journal=Dev. Dyn. |volume=227 |issue= 4 |pages= 608-14 |year= 2004 |pmid= 12889071 |doi= 10.1002/dvdy.10344
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ramos VC, Vidal-Taboada J, Bergoñon S, "et al." |title=Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21. |journal=Biochim. Biophys. Acta |volume=1577 |issue= 3 |pages= 377-83 |year= 2002 |pmid= 12359327 |doi=
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311-9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Vidal-Taboada JM, Bergoñón S, Sánchez M, "et al." |title=High resolution physical mapping and identification of transcribed sequences in the Down syndrome region-2. |journal=Biochem. Biophys. Res. Commun. |volume=243 |issue= 2 |pages= 572-8 |year= 1998 |pmid= 9480850 |doi= 10.1006/bbrc.1998.8141
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=

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