- ALDH6A1
Aldehyde dehydrogenase 6 family, member A1, also known as ALDH6A1, is a human
gene .cite web | title = Entrez Gene: ALDH6A1 aldehyde dehydrogenase 6 family, member A1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4329| accessdate = ]PBB_Summary
section_title =
summary_text = This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.cite web | title = Entrez Gene: ALDH6A1 aldehyde dehydrogenase 6 family, member A1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4329| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kuiper H, Spötter A, Williams JL, "et al." |title=Physical mapping of CHX10, ALDH6A1, and ABCD4 on bovine chromosome 10q34. |journal=Cytogenet. Genome Res. |volume=109 |issue= 4 |pages= 533 |year= 2005 |pmid= 15909363 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Anderson NL, Polanski M, Pieper R, "et al." |title=The human plasma proteome: a nonredundant list developed by combination of four separate sources. |journal=Mol. Cell Proteomics |volume=3 |issue= 4 |pages= 311–26 |year= 2004 |pmid= 14718574 |doi= 10.1074/mcp.M300127-MCP200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chambliss KL, Gray RG, Rylance G, "et al." |title=Molecular characterization of methylmalonate semialdehyde dehydrogenase deficiency. |journal=J. Inherit. Metab. Dis. |volume=23 |issue= 5 |pages= 497–504 |year= 2001 |pmid= 10947204 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Kedishvili NY, Popov KM, Rougraff PM, "et al." |title=CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution. |journal=J. Biol. Chem. |volume=267 |issue= 27 |pages= 19724–9 |year= 1992 |pmid= 1527093 |doi=PBB_Controls
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