TMEM158

Transmembrane protein 158, also known as TMEM158, is a human gene.cite web | title = Entrez Gene: TMEM158 transmembrane protein 158| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25907| accessdate = ]

PBB_Summary
section_title =
summary_text = Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway.cite web | title = Entrez Gene: TMEM158 transmembrane protein 158| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25907| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Iglesias D, Fernández-Peralta AM, Nejda N, "et al." |title=RIS1, a gene with trinucleotide repeats, is a target in the mutator pathway of colorectal carcinogenesis. |journal=Cancer Genet. Cytogenet. |volume=167 |issue= 2 |pages= 138–44 |year= 2006 |pmid= 16737913 |doi= 10.1016/j.cancergencyto.2005.12.002
*cite journal | author=Zirn B, Samans B, Wittmann S, "et al." |title=Target genes of the WNT/beta-catenin pathway in Wilms tumors. |journal=Genes Chromosomes Cancer |volume=45 |issue= 6 |pages= 565–74 |year= 2006 |pmid= 16575872 |doi= 10.1002/gcc.20319
*cite journal | author=Silva J, Silva JM, Barradas M, "et al." |title=Analysis of the candidate tumor suppressor Ris-1 in primary human breast carcinomas. |journal=Mutat. Res. |volume=594 |issue= 1-2 |pages= 78–85 |year= 2006 |pmid= 16280139 |doi= 10.1016/j.mrfmmm.2005.07.017
*cite journal | author=Sussan TE, Pletcher MT, Murakami Y, Reeves RH |title=Tumor suppressor in lung cancer 1 (TSLC1) alters tumorigenic growth properties and gene expression. |journal=Mol. Cancer |volume=4 |issue= |pages= 28 |year= 2006 |pmid= 16083501 |doi= 10.1186/1476-4598-4-28
*cite journal | author=Verlinden I, Janssens J, Raus J, Michiels L |title=Microdissection and SAGE as a combined tool to reveal gene expression in ductal carcinoma in situ of the breast. |journal=Mol. Carcinog. |volume=41 |issue= 4 |pages= 197–206 |year= 2005 |pmid= 15486950 |doi= 10.1002/mc.20055
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Barradas M, Gonos ES, Zebedee Z, "et al." |title=Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence. |journal=Exp. Cell Res. |volume=273 |issue= 2 |pages= 127–37 |year= 2002 |pmid= 11822868 |doi= 10.1006/excr.2001.5434
*cite journal | author=Hama T, Maruyama M, Katoh-Semba R, "et al." |title=Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival. |journal=J. Biol. Chem. |volume=276 |issue= 34 |pages= 31929–35 |year= 2001 |pmid= 11399754 |doi= 10.1074/jbc.M100617200

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