Simcyp — is a University of Sheffield spin out company that develop algorithms along with population and drug databases for modelling and simulation (M S) of the absorption and disposition of drugs in patients and specific subgroups of patients across… … Wikipedia
Physiologically-based pharmacokinetic modelling — Physiologically based pharmacokinetic modeling (PBPK) is a mathematical modeling technique for prediction of the absorption, distribution, metabolization and excretion (ADME) of a compound in humans and other animal species. PBPK modeling is used … Wikipedia
Physiologically based pharmacokinetic modelling — Contents 1 What is a PBPK model? 2 History 3 Uses of PBPK modeling 4 Limits and extensions of PBPK modeling … Wikipedia
Modelado PBPK — Estructura de ejemplo de un Modelo PBPK. El modelado farmacocinético fisiologicamente basado (Modelado PBPK por sus siglas en inglés) es una técnica de modelamiento matemático de la farmacocinética para predecir la absorción, distribución,… … Wikipedia Español
Drug discovery — In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identifying the active ingredient from traditional… … Wikipedia
ADME — is an acronym in pharmacokinetics and pharmacology for absorption, distribution, metabolism, and excretion, and describes the disposition of a pharmaceutical compound within an organism. The four criteria all influence the drug levels and… … Wikipedia
Pre-clinical development — is a stage of research that begins before clinical trials (testing in humans) can begin, and during which important feasibility, iterative testing and safety (also known as Good Laboratory Practice or GLP ) data is collected. The main goals of… … Wikipedia
Pharmacokinetics simulation — is a simulation method used in determining the safety levels of a drug during its development. It gives an insight to drug efficacy and safety before exposure of individuals to the new drug that might help to improve the design of a clinical… … Wikipedia
