Sommelet reaction

Sommelet reaction

The Sommelet reaction is an organic reaction in which a benzyl halide is converted to an aldehyde by action of hexamine and water [cite journal
journal = Compt. rend.
title = Sur un mode de décomposition des halogénoalcoylates d'hexaméthylène - tétramine
author = Marcel Sommelet
volume = 157
pages = 852–854
year = 1913
url = http://gallica.bnf.fr/ark:/12148/bpt6k31103/f852.table
] [JerryMarch] [For an example see: Organic Syntheses, Coll. Vol. 4, p.918 (1963); Vol. 33, p.93 (1953). http://www.orgsynth.org/orgsyn/pdfs/CV4P0918.pdf] .

:A conceptually related reaction is the Duff reaction (halide replaced by an arene).

In the Kröhnke aldehyde synthesis [F. Kröhnke, Ber., 71B, 2583 (1938).] the oxidizing reagent is is a combination of pyridine and p-nitrosodimethylaniline.

References


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