GAD2

GAD2

Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), also known as GAD2, is a human gene.

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summary_text = This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. [cite web | title = Entrez Gene: GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2572| accessdate = ]

ee also

* Glutamate decarboxylase

References

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