Binding coefficient

Binding coefficient

In medicinal chemistry and pharmacology, a binding coefficient is a quantity representing the extent to which a chemical compound will bind to a macromolecule. [Schurr JM, Rangel DP, Aragon SR. (2005) [http://www.biophysj.org/cgi/content/full/89/4/2258 "A Contribution to the Theory of Preferential Interaction Coefficients."] "Biophysical Journal." 89:2258-2276.] [Shulgin IL, Ruckenstein E (2006) [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1367075 "A Protein Molecule in a Mixed Solvent: The Preferential Binding Parameter via the Kirkwood-Buff Theory."] "Biophysical Journal." 90:704–707.]

See also

* Binding constant
* Partition coefficient

References


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  • binding coefficient — ryšio koeficientas statusas T sritis fizika atitikmenys: angl. binding coefficient; binding fraction vok. Bindungskoeffizient, m rus. коэффициент связи, m pranc. coefficient de liaison, m …   Fizikos terminų žodynas

  • binding fraction — ryšio koeficientas statusas T sritis fizika atitikmenys: angl. binding coefficient; binding fraction vok. Bindungskoeffizient, m rus. коэффициент связи, m pranc. coefficient de liaison, m …   Fizikos terminų žodynas

  • coefficient de liaison — ryšio koeficientas statusas T sritis fizika atitikmenys: angl. binding coefficient; binding fraction vok. Bindungskoeffizient, m rus. коэффициент связи, m pranc. coefficient de liaison, m …   Fizikos terminų žodynas

  • Binding potential — In pharmacokinetics and receptor ligand kinetics the binding potential (BP) is a combined measure of the density of available neuroreceptors and the affinity of a drug to that neuroreceptor. Description Consider a ligand receptor binding system.… …   Wikipedia

  • binding fraction — ryšio koeficientas statusas T sritis Standartizacija ir metrologija apibrėžtis Apibrėžtį žr. priede. priedas( ai) Grafinis formatas atitikmenys: angl. binding fraction vok. Koppelfaktor, m; Koppelungsfaktor, m; Koppelungskoeffizient, m rus.… …   Penkiakalbis aiškinamasis metrologijos terminų žodynas

  • coefficient de cohésion — ryšio koeficientas statusas T sritis Standartizacija ir metrologija apibrėžtis Apibrėžtį žr. priede. priedas( ai) Grafinis formatas atitikmenys: angl. binding fraction vok. Koppelfaktor, m; Koppelungsfaktor, m; Koppelungskoeffizient, m rus.… …   Penkiakalbis aiškinamasis metrologijos terminų žodynas

  • coefficient de liaison — ryšio koeficientas statusas T sritis Standartizacija ir metrologija apibrėžtis Apibrėžtį žr. priede. priedas( ai) Grafinis formatas atitikmenys: angl. binding fraction vok. Koppelfaktor, m; Koppelungsfaktor, m; Koppelungskoeffizient, m rus.… …   Penkiakalbis aiškinamasis metrologijos terminų žodynas

  • Partition coefficient — In chemistry and the pharmaceutical sciences, a partition (P) or distribution coefficient (D) is the ratio of concentrations of a compound in the two phases of a mixture of two immiscible solvents at equilibrium.[1] The terms gas/liquid partition …   Wikipedia

  • Cooperative binding — In biochemistry, a macromolecule exhibits cooperative binding if its affinity for its ligand changes with the amount of ligand already bound. Cooperative binding is a special case of allostery. Cooperative binding requires that the macromolecule… …   Wikipedia

  • Hill coefficient — A measure of cooperativity in a binding process. A Hill coefficient of 1 indicates independent binding, a value of greater than 1 shows positive cooperativity binding of one ligand facilitates binding of subsequent ligands at other sites on the… …   Dictionary of molecular biology

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