- CRB3
Crumbs homolog 3 (Drosophila), also known as CRB3, is a human
gene .cite web | title = Entrez Gene: CRB3 crumbs homolog 3 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92359| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.cite web | title = Entrez Gene: CRB3 crumbs homolog 3 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92359| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Lemmers C, Médina E, Delgrossi MH, "et al." |title=hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells. |journal=J. Biol. Chem. |volume=277 |issue= 28 |pages= 25408–15 |year= 2002 |pmid= 11964389 |doi= 10.1074/jbc.M202196200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Makarova O, Roh MH, Liu CJ, "et al." |title=Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1). |journal=Gene |volume=302 |issue= 1-2 |pages= 21–9 |year= 2003 |pmid= 12527193 |doi=
*cite journal | author=Roh MH, Fan S, Liu CJ, Margolis B |title=The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells. |journal=J. Cell. Sci. |volume=116 |issue= Pt 14 |pages= 2895–906 |year= 2004 |pmid= 12771187 |doi= 10.1242/jcs.00500
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Lemmers C, Michel D, Lane-Guermonprez L, "et al." |title=CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells. |journal=Mol. Biol. Cell |volume=15 |issue= 3 |pages= 1324–33 |year= 2004 |pmid= 14718572 |doi= 10.1091/mbc.E03-04-0235
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Fogg VC, Liu CJ, Margolis B |title=Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells. |journal=J. Cell. Sci. |volume=118 |issue= Pt 13 |pages= 2859–69 |year= 2005 |pmid= 15976445 |doi= 10.1242/jcs.02412
*cite journal | author=Fan S, Fogg V, Wang Q, "et al." |title=A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions. |journal=J. Cell Biol. |volume=178 |issue= 3 |pages= 387–98 |year= 2007 |pmid= 17646395 |doi= 10.1083/jcb.200609096PBB_Controls
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