CCNG2

Cyclin G2, also known as CCNG2, is a human gene.cite web | title = Entrez Gene: CCNG2 cyclin G2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=901| accessdate = ]

PBB_Summary
section_title =
summary_text = The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.cite web | title = Entrez Gene: CCNG2 cyclin G2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=901| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Horne MC, Goolsby GL, Donaldson KL, "et al." |title=Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression. |journal=J. Biol. Chem. |volume=271 |issue= 11 |pages= 6050–61 |year= 1996 |pmid= 8626390 |doi=
*cite journal | author=Bates S, Rowan S, Vousden KH |title=Characterisation of human cyclin G1 and G2: DNA damage inducible genes. |journal=Oncogene |volume=13 |issue= 5 |pages= 1103–9 |year= 1996 |pmid= 8806701 |doi=
*cite journal | author=Bennin DA, Don AS, Brake T, "et al." |title=Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. |journal=J. Biol. Chem. |volume=277 |issue= 30 |pages= 27449–67 |year= 2002 |pmid= 11956189 |doi= 10.1074/jbc.M111693200
*cite journal | author=Tian YL, Liu FR, Liu J, "et al." |title= [Ectopic expression of cyclin G2 inhibits cell proliferation in HeLa cancer cell line] |journal=Ai Zheng |volume=21 |issue= 6 |pages= 577–81 |year= 2003 |pmid= 12452053 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Bergqvist M, Brattström D, Brodin D, "et al." |title=Genes associated with telomerase activity levels in esophageal carcinoma cell lines. |journal=Dis. Esophagus |volume=19 |issue= 1 |pages= 20–3 |year= 2006 |pmid= 16364039 |doi= 10.1111/j.1442-2050.2006.00532.x
*cite journal | author=Stossi F, Likhite VS, Katzenellenbogen JA, Katzenellenbogen BS |title=Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter. |journal=J. Biol. Chem. |volume=281 |issue= 24 |pages= 16272–8 |year= 2006 |pmid= 16608856 |doi= 10.1074/jbc.M513405200
*cite journal | author=Arachchige Don AS, Dallapiazza RF, Bennin DA, "et al." |title=Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest. |journal=Exp. Cell Res. |volume=312 |issue= 20 |pages= 4181–204 |year= 2007 |pmid= 17123511 |doi= 10.1016/j.yexcr.2006.09.023

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