Fischer oxazole synthesis

Fischer oxazole synthesis

The Fischer oxazole synthesis is a chemical synthesis of the aromatic heterocycle oxazole from cyanohydrins and aldehydes in the presence of anhydrous hydrochloric acid. This method was discovered by Hermann Emil Fischer in 1896.

References

*Fischer, E. "Ber." 1896, "29", 205.
*Wiley, R. H. "Chem. Rev." 1945, "37", 401.


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