MRPS26

MRPS26

Mitochondrial ribosomal protein S26, also known as MRPS26, is a human gene.cite web | title = Entrez Gene: MRPS26 mitochondrial ribosomal protein S26| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64949| accessdate = ]

PBB_Summary
section_title =
summary_text = Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene.cite web | title = Entrez Gene: MRPS26 mitochondrial ribosomal protein S26| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64949| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Goldschmidt-Reisin S, Kitakawa M, Herfurth E, "et al." |title=Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences. |journal=J. Biol. Chem. |volume=273 |issue= 52 |pages= 34828–36 |year= 1999 |pmid= 9857009 |doi=
*cite journal | author=Cavdar Koc E, Burkhart W, Blackburn K, "et al." |title=The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 19363–74 |year= 2001 |pmid= 11279123 |doi= 10.1074/jbc.M100727200
*cite journal | author=Kenmochi N, Suzuki T, Uechi T, "et al." |title=The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. |journal=Genomics |volume=77 |issue= 1-2 |pages= 65–70 |year= 2001 |pmid= 11543634 |doi= 10.1006/geno.2001.6622
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhang Z, Gerstein M |title=Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. |journal=Genomics |volume=81 |issue= 5 |pages= 468–80 |year= 2003 |pmid= 12706105 |doi=
*cite journal | author=Scanlan MJ, Gout I, Gordon CM, "et al." |title=Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. |journal=Cancer Immun. |volume=1 |issue= |pages= 4 |year= 2003 |pmid= 12747765 |doi=
*cite journal | author=Ishiguchi H, Izumi H, Torigoe T, "et al." |title=ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA. |journal=Int. J. Cancer |volume=111 |issue= 6 |pages= 900–9 |year= 2004 |pmid= 15300802 |doi= 10.1002/ijc.20358
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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  • Ribosomal RNA — (rRNA) is the central component of the ribosome, the protein manufacturing machinery of all living cells. The function of the rRNA is to provide a mechanism for decoding mRNA into amino acids and to interact with the tRNAs during translation by… …   Wikipedia

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