ABCG4

ABCG4

ATP-binding cassette, sub-family G (WHITE), member 4, also known as ABCG4, is a human gene.cite web | title = Entrez Gene: ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64137| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.cite web | title = Entrez Gene: ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64137| accessdate = ]

ee also

* ATP-binding cassette transporter

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Dean M, Rzhetsky A, Allikmets R |title=The human ATP-binding cassette (ABC) transporter superfamily. |journal=Genome Res. |volume=11 |issue= 7 |pages= 1156–66 |year= 2001 |pmid= 11435397 |doi= 10.1101/gr.184901
*cite journal | author=Engel T, Lorkowski S, Lueken A, "et al." |title=The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages. |journal=Biochem. Biophys. Res. Commun. |volume=288 |issue= 2 |pages= 483–8 |year= 2001 |pmid= 11606068 |doi= 10.1006/bbrc.2001.5756
*cite journal | author=Annilo T, Tammur J, Hutchinson A, "et al." |title=Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4. |journal=Cytogenet. Cell Genet. |volume=94 |issue= 3-4 |pages= 196–201 |year= 2002 |pmid= 11856881 |doi=
*cite journal | author=Yoshikawa M, Yabuuchi H, Kuroiwa A, "et al." |title=Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4. |journal=Gene |volume=293 |issue= 1-2 |pages= 67–75 |year= 2002 |pmid= 12137944 |doi=
*cite journal | author=Oldfield S, Lowry C, Ruddick J, Lightman S |title=ABCG4: a novel human white family ABC-transporter expressed in the brain and eye. |journal=Biochim. Biophys. Acta |volume=1591 |issue= 1-3 |pages= 175–9 |year= 2002 |pmid= 12183068 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cserepes J, Szentpétery Z, Seres L, "et al." |title=Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization. |journal=Biochem. Biophys. Res. Commun. |volume=320 |issue= 3 |pages= 860–7 |year= 2004 |pmid= 15240127 |doi= 10.1016/j.bbrc.2004.06.037
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Engel T, Bode G, Lueken A, "et al." |title=Expression and functional characterization of ABCG1 splice variant ABCG1(666). |journal=FEBS Lett. |volume=580 |issue= 18 |pages= 4551–9 |year= 2006 |pmid= 16870176 |doi= 10.1016/j.febslet.2006.07.006
*cite journal | author=Vaughan AM, Oram JF |title=ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL. |journal=J. Lipid Res. |volume=47 |issue= 11 |pages= 2433–43 |year= 2007 |pmid= 16902247 |doi= 10.1194/jlr.M600218-JLR200

External links

*

[Category:Solute carrier family]

PBB_Controls
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update_protein_box = yes
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