ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1, also known as ABCG1, is a human gene.cite web | title = Entrez Gene: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9619| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have been identified.cite web | title = Entrez Gene: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9619| accessdate = ]

ee also

* ATP-binding cassette transporter

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schmitz G, Langmann T, Heimerl S |title=Role of ABCG1 and other ABCG family members in lipid metabolism. |journal=J. Lipid Res. |volume=42 |issue= 10 |pages= 1513–20 |year= 2002 |pmid= 11590207 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Chen H, Rossier C, Lalioti MD, "et al." |title=Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3. |journal=Am. J. Hum. Genet. |volume=59 |issue= 1 |pages= 66–75 |year= 1996 |pmid= 8659545 |doi=
*cite journal | author=Savary S, Denizot F, Luciani M, "et al." |title=Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene. |journal=Mamm. Genome |volume=7 |issue= 9 |pages= 673–6 |year= 1996 |pmid= 8703120 |doi=
*cite journal | author=Croop JM, Tiller GE, Fletcher JA, "et al." |title=Isolation and characterization of a mammalian homolog of the Drosophila white gene. |journal=Gene |volume=185 |issue= 1 |pages= 77–85 |year= 1997 |pmid= 9034316 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Klucken J, Büchler C, Orsó E, "et al." |title=ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 2 |pages= 817–22 |year= 2000 |pmid= 10639163 |doi=
*cite journal | author=Venkateswaran A, Repa JJ, Lobaccaro JM, "et al." |title=Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols. |journal=J. Biol. Chem. |volume=275 |issue= 19 |pages= 14700–7 |year= 2000 |pmid= 10799558 |doi=
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Berry A, Scott HS, Kudoh J, "et al." |title=Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region. |journal=Genomics |volume=68 |issue= 1 |pages= 22–9 |year= 2001 |pmid= 10950923 |doi= 10.1006/geno.2000.6253
*cite journal | author=Langmann T, Porsch-Ozcürümez M, Unkelbach U, "et al." |title=Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene. |journal=Biochim. Biophys. Acta |volume=1494 |issue= 1-2 |pages= 175–80 |year= 2000 |pmid= 11072082 |doi=
*cite journal | author=Lorkowski S, Rust S, Engel T, "et al." |title=Genomic sequence and structure of the human ABCG1 (ABC8) gene. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 1 |pages= 121–31 |year= 2001 |pmid= 11162488 |doi= 10.1006/bbrc.2000.4089
*cite journal | author=Porsch-Ozcurumez M, Langmann T, Heimerl S, "et al." |title=The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux. |journal=J. Biol. Chem. |volume=276 |issue= 15 |pages= 12427–33 |year= 2001 |pmid= 11279031 |doi= 10.1074/jbc.M100218200
*cite journal | author=Lorkowski S, Kratz M, Wenner C, "et al." |title=Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease. |journal=Biochem. Biophys. Res. Commun. |volume=283 |issue= 4 |pages= 821–30 |year= 2001 |pmid= 11350058 |doi= 10.1006/bbrc.2001.4863
*cite journal | author=Kennedy MA, Venkateswaran A, Tarr PT, "et al." |title=Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 39438–47 |year= 2001 |pmid= 11500512 |doi= 10.1074/jbc.M105863200
*cite journal | author=Kaplan R, Gan X, Menke JG, "et al." |title=Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway. |journal=J. Lipid Res. |volume=43 |issue= 6 |pages= 952–9 |year= 2003 |pmid= 12032171 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Cserepes J, Szentpétery Z, Seres L, "et al." |title=Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization. |journal=Biochem. Biophys. Res. Commun. |volume=320 |issue= 3 |pages= 860–7 |year= 2004 |pmid= 15240127 |doi= 10.1016/j.bbrc.2004.06.037

External links

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