WNT16

Wingless-type MMTV integration site family, member 16, also known as WNT16, is a human gene.cite web | title = Entrez Gene: WNT16 wingless-type MMTV integration site family, member 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51384| accessdate = ]

PBB_Summary
section_title =
summary_text = The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.cite web | title = Entrez Gene: WNT16 wingless-type MMTV integration site family, member 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51384| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Smolich BD, McMahon JA, McMahon AP, Papkoff J |title=Wnt family proteins are secreted and associated with the cell surface. |journal=Mol. Biol. Cell |volume=4 |issue= 12 |pages= 1267–75 |year= 1994 |pmid= 8167409 |doi=
*cite journal | author=McWhirter JR, Neuteboom ST, Wancewicz EV, "et al." |title=Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 20 |pages= 11464–9 |year= 1999 |pmid= 10500199 |doi=
*cite journal | author=Fear MW, Kelsell DP, Spurr NK, Barnes MR |title=Wnt-16a, a novel Wnt-16 isoform, which shows differential expression in adult human tissues. |journal=Biochem. Biophys. Res. Commun. |volume=278 |issue= 3 |pages= 814–20 |year= 2001 |pmid= 11095990 |doi= 10.1006/bbrc.2000.3852
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Katoh Y, Katoh M |title=Comparative genomics on Wnt16 orthologs. |journal=Oncol. Rep. |volume=13 |issue= 4 |pages= 771–5 |year= 2005 |pmid= 15756456 |doi=
*cite journal | author=Mazieres J, You L, He B, "et al." |title=Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. |journal=Oncogene |volume=24 |issue= 34 |pages= 5396–400 |year= 2005 |pmid= 16007226 |doi= 10.1038/sj.onc.1208568
*cite journal | author=Casagrande G, te Kronnie G, Basso G |title=The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line. |journal=Haematologica |volume=91 |issue= 6 |pages= 765–71 |year= 2006 |pmid= 16769578 |doi=

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