KCNJ9

KCNJ9

Potassium inwardly-rectifying channel, subfamily J, member 9, also known as KCNJ9, is a human gene.cite web | title = Entrez Gene: KCNJ9 potassium inwardly-rectifying channel, subfamily J, member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3765| accessdate = ]

PBB_Summary
section_title =
summary_text = Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex.cite web | title = Entrez Gene: KCNJ9 potassium inwardly-rectifying channel, subfamily J, member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3765| accessdate = ]

ee also

* G protein-coupled inwardly-rectifying potassium channel
* Inward-rectifier potassium ion channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kubo Y, Adelman JP, Clapham DE, "et al." |title=International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 509–26 |year= 2006 |pmid= 16382105 |doi= 10.1124/pr.57.4.11
*cite journal | author=Lesage F, Fink M, Barhanin J, "et al." |title=Assignment of human G-protein-coupled inward rectifier K+ channel homolog GIRK3 gene to chromosome 1q21-q23. |journal=Genomics |volume=29 |issue= 3 |pages= 808–9 |year= 1996 |pmid= 8575783 |doi= 10.1006/geno.1995.9928
*cite journal | author=Jelacic TM, Sims SM, Clapham DE |title=Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3. |journal=J. Membr. Biol. |volume=169 |issue= 2 |pages= 123–9 |year= 1999 |pmid= 10341034 |doi=
*cite journal | author=Schoots O, Wilson JM, Ethier N, "et al." |title=Co-expression of human Kir3 subunits can yield channels with different functional properties. |journal=Cell. Signal. |volume=11 |issue= 12 |pages= 871–83 |year= 2000 |pmid= 10659995 |doi=
*cite journal | author=Vaughn J, Wolford JK, Prochazka M, Permana PA |title=Genomic structure and expression of human KCNJ9 (Kir3.3/GIRK3). |journal=Biochem. Biophys. Res. Commun. |volume=274 |issue= 2 |pages= 302–9 |year= 2000 |pmid= 10913335 |doi= 10.1006/bbrc.2000.3136
*cite journal | author=Jelacic TM, Kennedy ME, Wickman K, Clapham DE |title=Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36211–6 |year= 2000 |pmid= 10956667 |doi= 10.1074/jbc.M007087200
*cite journal | author=Lavine N, Ethier N, Oak JN, "et al." |title=G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase. |journal=J. Biol. Chem. |volume=277 |issue= 48 |pages= 46010–9 |year= 2003 |pmid= 12297500 |doi= 10.1074/jbc.M205035200
*cite journal | author=Plummer HK, Dhar MS, Cekanova M, Schuller HM |title=Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines. |journal=BMC Cancer |volume=5 |issue= |pages= 104 |year= 2006 |pmid= 16109170 |doi= 10.1186/1471-2407-5-104
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

External links

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  • G protein-coupled inwardly-rectifying potassium channel — protein Name = potassium inwardly rectifying channel, subfamily J, member 3 caption = width = HGNCid = 6264 Symbol = KCNJ3 AltSymbols = Kir3.1, GIRK1, KGA EntrezGene = 3760 OMIM = 601534 RefSeq = NM 002239 UniProt = P48549 PDB = ECnumber =… …   Wikipedia

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