CLEC2D

C-type lectin domain family 2, member D, also known as CLEC2D, is a human gene.cite web | title = Entrez Gene: CLEC2D C-type lectin domain family 2, member D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29121| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined.cite web | title = Entrez Gene: CLEC2D C-type lectin domain family 2, member D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29121| accessdate = ] CLEC2D encodes the gene for the Lectin Like Transcript-1 (LLT1) protein which is a functional ligand for the human NKR-P1A receptor, encoded by the KLRB1 gene.

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Boles KS, Barten R, Kumaresan PR, "et al." |title=Cloning of a new lectin-like receptor expressed on human NK cells. |journal=Immunogenetics |volume=50 |issue= 1-2 |pages= 1–7 |year= 1999 |pmid= 10541800 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Iizuka K, Naidenko OV, Plougastel BF, "et al." |title=Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors. |journal=Nat. Immunol. |volume=4 |issue= 8 |pages= 801–7 |year= 2003 |pmid= 12858173 |doi= 10.1038/ni954
*cite journal | author=Hu YS, Zhou H, Myers D, "et al." |title=Isolation of a human homolog of osteoclast inhibitory lectin that inhibits the formation and function of osteoclasts. |journal=J. Bone Miner. Res. |volume=19 |issue= 1 |pages= 89–99 |year= 2004 |pmid= 14753741 |doi=
*cite journal | author=Carlyle JR, Jamieson AM, Gasser S, "et al." |title=Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 10 |pages= 3527–32 |year= 2004 |pmid= 14990792 |doi= 10.1073/pnas.0308304101
*cite journal | author=Mathew PA, Chuang SS, Vaidya SV, "et al." |title=The LLT1 receptor induces IFN-gamma production by human natural killer cells. |journal=Mol. Immunol. |volume=40 |issue= 16 |pages= 1157–63 |year= 2004 |pmid= 15104121 |doi=
*cite journal | author=Gange CT, Quinn JM, Zhou H, "et al." |title=Characterization of sugar binding by osteoclast inhibitory lectin. |journal=J. Biol. Chem. |volume=279 |issue= 28 |pages= 29043–9 |year= 2004 |pmid= 15123656 |doi= 10.1074/jbc.M312518200
*cite journal | author=Aldemir H, Prod'homme V, Dumaurier MJ, "et al." |title=Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor. |journal=J. Immunol. |volume=175 |issue= 12 |pages= 7791–5 |year= 2006 |pmid= 16339512 |doi=
*cite journal | author=Rosen DB, Bettadapura J, Alsharifi M, "et al." |title=Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. |journal=J. Immunol. |volume=175 |issue= 12 |pages= 7796–9 |year= 2006 |pmid= 16339513 |doi=
*cite journal | author=Rosen, DB, Cao W, "et al." |title=Functional Consequences of Interactions between Human NKR-P1A and Its Ligand LLT1 Expressed on Activated Dendritic Cells and B Cells. |journal=J. Immunol. |volume=180 |issue=10 |pages= 6508-6517 |year= 2008 |pmid= 18453569 |doi=

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