SOSTDC1

Sclerostin domain containing 1, also known as SOSTDC1, is a human gene.cite web | title = Entrez Gene: SOSTDC1 sclerostin domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25928| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.cite web | title = Entrez Gene: SOSTDC1 sclerostin domain containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25928| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yanagita M |title=BMP antagonists: their roles in development and involvement in pathophysiology. |journal=Cytokine Growth Factor Rev. |volume=16 |issue= 3 |pages= 309–17 |year= 2006 |pmid= 15951218 |doi= 10.1016/j.cytogfr.2005.02.007
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Laurikkala J, Kassai Y, Pakkasjärvi L, "et al." |title=Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. |journal=Dev. Biol. |volume=264 |issue= 1 |pages= 91–105 |year= 2004 |pmid= 14623234 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Yanagita M, Oka M, Watabe T, "et al." |title=USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney. |journal=Biochem. Biophys. Res. Commun. |volume=316 |issue= 2 |pages= 490–500 |year= 2004 |pmid= 15020244 |doi= 10.1016/j.bbrc.2004.02.075
*cite journal | author=Goto M, Eddy EM |title=Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20. |journal=J. Biol. Chem. |volume=279 |issue= 40 |pages= 42128–38 |year= 2004 |pmid= 15280373 |doi= 10.1074/jbc.M403190200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

PBB_Controls
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update_citations = yes