- PPIE (gene)
Peptidylprolyl isomerase E (cyclophilin E), also known as PPIE, is a human
gene .cite web | title = Entrez Gene: PPIE peptidylprolyl isomerase E (cyclophilin E)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10450| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.cite web | title = Entrez Gene: PPIE peptidylprolyl isomerase E (cyclophilin E)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10450| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Mi H, Kops O, Zimmermann E, "et al." |title=A nuclear RNA-binding cyclophilin in human T cells. |journal=FEBS Lett. |volume=398 |issue= 2-3 |pages= 201–5 |year= 1997 |pmid= 8977107 |doi=
*cite journal | author=Kim JO, Nau MM, Allikian KA, "et al." |title=Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines. |journal=Oncogene |volume=17 |issue= 8 |pages= 1019–26 |year= 1998 |pmid= 9747881 |doi= 10.1038/sj.onc.1202006
*cite journal | author=Fair K, Anderson M, Bulanova E, "et al." |title=Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells. |journal=Mol. Cell. Biol. |volume=21 |issue= 10 |pages= 3589–97 |year= 2001 |pmid= 11313484 |doi= 10.1128/MCB.21.10.3589-3597.2001
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727PBB_Controls
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