- SNUPN
Snurportin 1, also known as SNUPN, is a human
gene .cite web | title = Entrez Gene: SNUPN snurportin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10073| accessdate = ]PBB_Summary
section_title =
summary_text = The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.cite web | title = Entrez Gene: SNUPN snurportin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10073| accessdate = ]References
Further reading
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citations =
*cite journal | author=Huber J, Cronshagen U, Kadokura M, "et al." |title=Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure. |journal=EMBO J. |volume=17 |issue= 14 |pages= 4114–26 |year= 1998 |pmid= 9670026 |doi= 10.1093/emboj/17.14.4114
*cite journal | author=Paraskeva E, Izaurralde E, Bischoff FR, "et al." |title=CRM1-mediated recycling of snurportin 1 to the cytoplasm. |journal=J. Cell Biol. |volume=145 |issue= 2 |pages= 255–64 |year= 1999 |pmid= 10209022 |doi=
*cite journal | author=Narayanan U, Ospina JK, Frey MR, "et al." |title=SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta. |journal=Hum. Mol. Genet. |volume=11 |issue= 15 |pages= 1785–95 |year= 2003 |pmid= 12095920 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Strasser A, Dickmanns A, Lührmann R, Ficner R |title=Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1. |journal=EMBO J. |volume=24 |issue= 13 |pages= 2235–43 |year= 2005 |pmid= 15920472 |doi= 10.1038/sj.emboj.7600701
*cite journal | author=Ospina JK, Gonsalvez GB, Bednenko J, "et al." |title=Cross-talk between snurportin1 subdomains. |journal=Mol. Biol. Cell |volume=16 |issue= 10 |pages= 4660–71 |year= 2006 |pmid= 16030253 |doi= 10.1091/mbc.E05-04-0316
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029PBB_Controls
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