ALX1

Cartilage paired-class homeoprotein 1, also known as CART1, is a human gene.cite web | title = Entrez Gene: CART1 cartilage paired-class homeoprotein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8092| accessdate = ]

PBB_Summary
section_title =
summary_text = The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.cite web | title = Entrez Gene: CART1 cartilage paired-class homeoprotein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8092| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Régnier CH, Tomasetto C, Moog-Lutz C, "et al." |title=Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma. |journal=J. Biol. Chem. |volume=270 |issue= 43 |pages= 25715–21 |year= 1995 |pmid= 7592751 |doi=
*cite journal | author=Zhao GQ, Zhou X, Eberspaecher H, "et al." |title=Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 18 |pages= 8633–7 |year= 1993 |pmid= 7690966 |doi=
*cite journal | author=Zhao Q, Behringer RR, de Crombrugghe B |title=Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. |journal=Nat. Genet. |volume=13 |issue= 3 |pages= 275–83 |year= 1996 |pmid= 8673125 |doi= 10.1038/ng0796-275
*cite journal | author=Gordon DF, Wagner J, Atkinson BL, "et al." |title=Human Cart-1: structural organization, chromosomal localization, and functional analysis of a cartilage-specific homeodomain cDNA. |journal=DNA Cell Biol. |volume=15 |issue= 7 |pages= 531–41 |year= 1996 |pmid= 8756334 |doi=
*cite journal | author=Cai RL |title=Human CART1, a paired-class homeodomain protein, activates transcription through palindromic binding sites. |journal=Biochem. Biophys. Res. Commun. |volume=250 |issue= 2 |pages= 305–11 |year= 1998 |pmid= 9753625 |doi= 10.1006/bbrc.1998.9257
*cite journal | author=Qu S, Tucker SC, Zhao Q, "et al." |title=Physical and genetic interactions between Alx4 and Cart1. |journal=Development |volume=126 |issue= 2 |pages= 359–69 |year= 1999 |pmid= 9847249 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Iioka T, Furukawa K, Yamaguchi A, "et al." |title=P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain. |journal=J. Bone Miner. Res. |volume=18 |issue= 8 |pages= 1419–29 |year= 2004 |pmid= 12929931 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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