WNT9A

WNT9A

Wingless-type MMTV integration site family, member 9A, also known as WNT9A, is a human gene.cite web | title = Entrez Gene: WNT9A wingless-type MMTV integration site family, member 9A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7483| accessdate = ]

PBB_Summary
section_title =
summary_text = The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region.cite web | title = Entrez Gene: WNT9A wingless-type MMTV integration site family, member 9A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7483| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Smolich BD, McMahon JA, McMahon AP, Papkoff J |title=Wnt family proteins are secreted and associated with the cell surface. |journal=Mol. Biol. Cell |volume=4 |issue= 12 |pages= 1267–75 |year= 1994 |pmid= 8167409 |doi=
*cite journal | author=Bergstein I, Eisenberg LM, Bhalerao J, "et al." |title=Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. |journal=Genomics |volume=46 |issue= 3 |pages= 450–8 |year= 1998 |pmid= 9441749 |doi= 10.1006/geno.1997.5041
*cite journal | author=Hartmann C, Tabin CJ |title=Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. |journal=Cell |volume=104 |issue= 3 |pages= 341–51 |year= 2001 |pmid= 11239392 |doi=
*cite journal | author=Saitoh T, Hirai M, Katoh M |title=Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region. |journal=Biochem. Biophys. Res. Commun. |volume=284 |issue= 5 |pages= 1168–75 |year= 2001 |pmid= 11414706 |doi= 10.1006/bbrc.2001.5105
*cite journal | author=Katoh M |title=Molecular cloning and expression of mouse Wnt14, and structural comparison between mouse Wnt14-Wnt3a gene cluster and human WNT14-WNT3A gene cluster. |journal=Int. J. Mol. Med. |volume=9 |issue= 3 |pages= 221–7 |year= 2002 |pmid= 11836627 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Qian J, Jiang Z, Li M, "et al." |title=Mouse Wnt9b transforming activity, tissue-specific expression, and evolution. |journal=Genomics |volume=81 |issue= 1 |pages= 34–46 |year= 2003 |pmid= 12573259 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Katoh Y, Katoh M |title=Comparative genomics on Wnt9a orthologs. |journal=Oncol. Rep. |volume=13 |issue= 5 |pages= 989–92 |year= 2005 |pmid= 15809769 |doi=
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Bhattacharyya S, Borthakur A, Dudeja PK, Tobacman JK |title=Carrageenan reduces bone morphogenetic protein-4 (BMP4) and activates the Wnt/beta-catenin pathway in normal human colonocytes. |journal=Dig. Dis. Sci. |volume=52 |issue= 10 |pages= 2766–74 |year= 2007 |pmid= 17429723 |doi= 10.1007/s10620-006-9531-4

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Wnt signaling pathway — The Wnt signaling pathway describes a complex network of proteins most well known for their roles in embryogenesis and cancer, but also involved in normal physiological processes in adult animals.cite journal | author = Lie DC, Colamarino SA,… …   Wikipedia

  • Dishevelled — specific domain Solution structure of the mouse Dvl 1 DEP domain based on the PDB 1fsh coordinates. Identifiers …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”