CYP4F12

Cytochrome P450, family 4, subfamily F, polypeptide 12, also known as CYP4F12, is a human gene.cite web | title = Entrez Gene: CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=66002| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.cite web | title = Entrez Gene: CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=66002| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Simpson AE |title=The cytochrome P450 4 (CYP4) family. |journal=Gen. Pharmacol. |volume=28 |issue= 3 |pages= 351–9 |year= 1997 |pmid= 9068972 |doi=
*cite journal | author=Knight JA, Fronk S, Haymond RE |title=Chemical basis and specificity of chemical screening tests for urinary vanilmandelic acid. |journal=Clin. Chem. |volume=21 |issue= 1 |pages= 130–3 |year= 1975 |pmid= 1116264 |doi=
*cite journal | author=Bylund J, Bylund M, Oliw EH |title=cDna cloning and expression of CYP4F12, a novel human cytochrome P450. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 3 |pages= 892–7 |year= 2001 |pmid= 11162607 |doi= 10.1006/bbrc.2000.4191
*cite journal | author=Hashizume T, Imaoka S, Hiroi T, "et al." |title=cDNA cloning and expression of a novel cytochrome p450 (cyp4f12) from human small intestine. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 4 |pages= 1135–41 |year= 2001 |pmid= 11162645 |doi= 10.1006/bbrc.2000.4238
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Stark K, Wongsud B, Burman R, Oliw EH |title=Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8. |journal=Arch. Biochem. Biophys. |volume=441 |issue= 2 |pages= 174–81 |year= 2005 |pmid= 16112640 |doi= 10.1016/j.abb.2005.07.003
*cite journal | author=Otsuki T, Ota T, Nishikawa T, "et al." |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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