- SAV1
Salvador homolog 1 (Drosophila), also known as SAV1, is a human
gene .cite web | title = Entrez Gene: SAV1 salvador homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60485| accessdate = ]PBB_Summary
section_title =
summary_text = WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.cite web | title = Entrez Gene: SAV1 salvador homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60485| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Valverde P |title=Cloning, expression, and mapping of hWW45, a novel human WW domain-containing gene. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 3 |pages= 990–8 |year= 2000 |pmid= 11027580 |doi= 10.1006/bbrc.2000.3582
*cite journal | author=Tapon N, Harvey KF, Bell DW, "et al." |title=salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. |journal=Cell |volume=110 |issue= 4 |pages= 467–78 |year= 2002 |pmid= 12202036 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yoo NJ, Soung YH, Lee JW, "et al." |title=Mutational analysis of salvador gene in human carcinomas. |journal=APMIS |volume=111 |issue= 6 |pages= 595–8 |year= 2003 |pmid= 12969014 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Chan EH, Nousiainen M, Chalamalasetty RB, "et al." |title=The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. |journal=Oncogene |volume=24 |issue= 12 |pages= 2076–86 |year= 2005 |pmid= 15688006 |doi= 10.1038/sj.onc.1208445
*cite journal | author=Benzinger A, Muster N, Koch HB, "et al." |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. |journal=Mol. Cell Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200
*cite journal | author=Callus BA, Verhagen AM, Vaux DL |title=Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. |journal=FEBS J. |volume=273 |issue= 18 |pages= 4264–76 |year= 2006 |pmid= 16930133 |doi= 10.1111/j.1742-4658.2006.05427.xPBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.
